The phosphate salt of codeine happens as white, needle-formed crystals or white crystalline powder. Codeine phosphate is freely soluble in h2o and marginally soluble in alcohol.
Having said that, codeine should be administered only less than shut supervision to clients with a record of drug abuse or dependence.
Codeine: In clients obtaining MAO inhibitors, an First small test dose is advisable to permit observation of any too much narcotic effects or MAOI conversation.
It is achievable to overdose on promethazine. Overdosing produces alarming signs or symptoms, for example seizures and severely small hypertension. Promethazine overdose is rarely lethal but using way too much is risky.
कुछ गंभीर स्थितियों वाले लोगों के लिए चेतावनी
प्रोमेथजिन इंजेक्शन का उपयोग कुछ स्थितियों में जी मिचलाने और उल्टी के इलाज के लिए किया जाता है (जैसे, सर्जरी के बाद, मोशन सिकनेस)। इसका उपयोग अन्य दवाओं के साथ जान के लिए खतरा बनने वाले एलर्जिक लक्षण (एनाफिलाक्सिस) और रक्त उत्पादों की प्रतिक्रियाओं के इलाज के लिए भी किया जाता है। जब आप गोली के रूप में इस दवाई को नहीं ले पाते हैं तो इंजेक्शन के रूप में इसका इस्तेमाल मध्यम एलर्जिक रिएक्शन के उपचार के लिए भी किया जाता है। इसका उपयोग सर्जरी से पहले या बाद में, अन्य प्रक्रियाओं या प्रसव और डिलिवरी में आपको ठीक रखने, उल्टी या मतली से बचाव करने के लिए किया जाता है।
Promethazine is metabolized from the liver to a number of compounds; the sulfoxides of promethazine and N-demethylpromethazine would be the predominant metabolites showing up within the urine.
A perhaps deadly symptom intricate in some cases often called Neuroleptic Malignant Syndrome (NMS) has long been described in association with promethazine HCl alone or in combination with antipsychotic drugs.
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Antihistamines and codeine are the two contraindicated for use from the treatment of decrease respiratory tract indicators, like asthma.
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